jvmbbs

Issue 1

Journal for Veterinary Medicine, Biotechnology and Biosafety

Volume 3, Issue 1, March 2017, Pages 26–31

ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)

BIOCHEmICAL PARAmETERS Of BLOOD SERum Of DOGS WITH HEPATIC LIPIDOSIS

Zemlyanskyi A. O.

Luhansk National Agrarian University, Kharkiv, Ukraine, e-mail: totty.toy007@gmail.com

Citation for print version: Zemlyanskyi, A. O. (2017) ‘Biochemical parameters of blood serum of dogs with Hepatic lipidosis’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 3(1), pp. 26–31.

Download PDF (online version)

Citation for online version: Zemlyanskyi, A. O. (2017) ‘Biochemical parameters of blood serum of dogs with Hepatic lipidosis’, Journal for Veterinary Medicine, Biotechnology and Biosafety. [Online] 3(1), pp. 26–31. Available at: http://jvmbbs.kharkov.ua/archive/2017/volume3/issue1/oJVMBBS_2017031_026-031.pdf

Summary. Dog hepatic dystrophy (hepatic lipidosis) is a disease that mostly arises from inappropriate conditions of keeping and feeding. Triacylglycerols (TG) are accumulated in hepatocytes due to variety of toxic influences, lack of carbohydrates in nutrient budget. One of the main mechanisms of lipidosis that accompanied by hyperlipidemia is increased accumulation of triacylglycerols (TG) on the background of reducing the rate of their removal. Dog’s fatty liver dystrophy is characterized by indistinct identify clinical features that requires using of laboratory and instrumental methods in diagnostics. Determination of lipid composition in dogs was not carried out in veterinary medicine practice in Ukraine although abnormalities of lipid metabolism play an important role in the development of liver lipidosis.

Keywords: dogs, liver, lipidosis, diagnostics, biochemical parameters, lipid diagram, treatment

References:

Afanas’ev, Yu. I. and Yurina, N. A. (eds.) (1999) Histology [Gistologiya]. 5^th ed. Moscow: Meditsina. ISBN 5225045235. [in Russian]

Alegre, B., Carrasco, D., Breto, M. D., Gras, M. and Berenguer, J. (1976) ‘Semiquantitative determination of lipoprotein X (Lp-X): its usefulness in differential diagnosis of jaundice’, Revista Clinica Espanola, 143(1), pp. 79–81

Bass, V. D., Hoffmann, W. E. and Dorner, J. L. (1976) ‘Normal canine lipid profiles and effects of experimentally induced pancreatitis and hepatic necrosis on lipids’, American Journal of Veterinary Research, 37(11), pp. 1355–1357

Boomkens, S. Y., Penning, L. C., Egberink, H. F., van den Ingh, T. S. G. A. M. and Rothuizen, J. (2004) ‘Hepatitis with special reference to dogs. A review on the pathogenesis and infectious etiologies, including unpublished results of recent own studies’, Veterinary Quarterly, 26(3), pp. 107–114. http://dx.doi.org10.1080/01652176.2004.9695174

Center, S. A. (1996) ‘Hepatic lipidosis, glucocorticoid hepatopathy, vacuolar hepatopathy, storage disorders, amyloidosis, and iron toxicity’, in Guilford, W.G., Center, S. A., Strombeck, D. R., Williams, D. A. and Meyer, D. J. (eds.) Strombeck’s small animal gastroenterology. Philadelphia, PA: W. B. Saunders, pp. 766–801. ISBN 9780721637600

Chub, O. V., Levchenko, V. I. and Sakhniuk, V. V. (2000) ‘The results chromatography of volatile fatty acids of highly productive cows’ [Rezultaty khromatohrafii letkykh zhyrnykh kyslot u vysokoproduktyvnykh koriv], Bulletin of the Bila Tserkva State Agrarian University [Visnyk Bilotserkivskoho derzhavnoho ahrarnoho universytetu], 13(2), pp. 182–188. [in Ukrainian]

Dykyi, O. A. (2000) Hepatic-dystrophy in dogs of service breeds (etiology, pathogenesis, diagnostics, treatment and prophylaxis) [Hepatodystrofiia u sobak sluzhbovykh porid (etiolohiia, patohenez, diahnostyka, likuvannia ta profilaktyka)]. The dissertation thesis for the scientific degree of the candidate of veterinary sciences. Bila Tserkva: Bila Tserkva National Agrarian University. [in Ukrainian]

Fasolya, V. P. (2008) ‘Diagnosis and treatment hepatopancreatic syndrome in dogs’ [Diahnostyka i likuvannia hepatopankreatychnoho syndromu v sobak], Scientific Messenger of Lviv National University of Veterinary Medicine and Biotechnologies named after S. Z. Gzhytskyj [Naukovyi visnyk Lvivskoho natsionalnoho universytetu veterynarnoi medytsyny ta biotekhnolohii imeni S. Z. Gzhytskoho], 10(2(37), 1), pp. 366–372. Available at: http://elibrary.ru/download/elibrary_25981817_79066598.pdf. [in Ukrainian]

Kamyshnikov, V. S. (2004) Handbook on clinical and biochemical research and laboratory diagnostics [Spravochnik po kliniko-biokhimicheskim issledovaniyam i laboratornoy diagnostike]. 2^nd ed. Moscow: MedPress-Inform. ISBN 5983220012. [in Russian]

Kirk, R. and Bonagura, D. (2005) Kirk’s Current Veterinary Therapy [Sovremennyy kurs veterinarnoy meditsiny Kirka]. Moscow: Akvarium. ISBN 9785423802912. [in Russian]

Levchenko, V. and Fasolja, V. (2008) ‘Spread of polimorbidinterual pathology in the dogs of service breeds’ [Poshyrennia mnozhynnoi vnutrishnoi patolohii u sobak sluzhbovykh porid ta yii patohenez], Scientific and Technical Bulletin of Institute of Animal Biology and State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives [Naukovo-tekhnichnyi biuleten Instytutu biolohii tvaryn i Derzhavnoho naukovo-doslidnoho kontrolnoho instytutu veterynarnykh preparativ ta kormovykh dobavok], 9(3), pp. 179–183. Available at: http://old.inenbiol.com/ntb/ntb2/pdf/3/2.pdf. [in Ukrainian]

Levchenko, V. I. (ed.) (2010) Methods of laboratory clinical diagnostics of animal diseases [Metody laboratornoi klinichnoi diahnostyky khvorob tvaryn]. Kyiv: Ahrarna osvita. ISBN 9789667906771. [in Ukrainian]

Levchenko, V. I. and Halias, V. L. (eds.) (2002) Veterinary clinical biochemistry [Veterynarna klinichna biokhimiia]. Bila Tserkva: Bila Tserkva State Agrarian University. ISBN 9667417409. [in Ukrainian]

Lokes, P. I. (2013) The pathology of the liver and urinary system in domestic dogs and cats (clinical and biochemical status, pathogenesis, diagnosis, treatment) [Patolohiia pechinky ta orhaniv sechovoi systemy u sviiskykh sobak i kotiv (kliniko-biokhimichnyi status, patohenez, diahnostyka, likuvannia)]. The dissertation thesis for the scientific degree of the doctor of veterinary sciences. Kyiv: The National University of Life and Environmental Sciences of Ukraine. [in Ukrainian]

Lokes, P. I., Stovba, V. H. and Karysheva, L. P. (2007) Ultrasound diagnosis of small animal diseases [Ultrazvukova diahnostyka khvorob dribnykh tvaryn]. Poltava: Poltava State Agrarian Academy. ISBN 9789662088052. [in Ukrainian]

Mahley, R. W., Hui, D. Y., Innerarity, T. L. and Weisgraber, K. H. (1981) ‘Two independent lipoprotein receptors on hepatic membranes of dog, swine, and man. Apo-B,E and apo-E receptors.’, Journal of Clinical Investigation, 68(5), pp. 1197–1206. http://dx.doi.org10.1172/JCI110365

Morozenko, D. V. and Timoshenko, O. P. (2012) ‘Biochemical indices of connective tissue in pathogenesis, diagnosis and control of treatment efficiency hepatopathy of dogs’ [Biokhimichni pokaznyky stanu spoluchnoi tkanyny u patohenezi, diahnostytsi ta kontroli efektyvnosti likuvannia hepatopatii sobak], The Animal Biology [Biolohiia tvaryn], 14(1–2), pp. 411–419. Available at: http://nbuv.gov.ua/UJRN/bitv_2012_14_1-2_67. [in Ukrainian]

Nazaruk, N., Hutiy, B. and Hufriy, D. (2012) ‘Features lipid peroxidation in the blood of the bullock affected by cadmium and nitrites’ [Osoblyvosti perekysnoho okysnennia lipidiv u krovi bychkiv, urazhenykh kadmiiem ta nitrytamy], Scientific and Technical Bulletin of Institute of Animal Biology and State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives [Naukovo-tekhnichnyi biuleten Instytutu biolohii tvaryn i Derzhavnoho naukovo-doslidnoho kontrolnoho instytutu veterynarnykh preparativ ta kormovykh dobavok], 13(3–4), pp. 250–254. Available at: http://old.inenbiol.com/ntb/ntb8/49.pdf. [in Ukrainian]

Rebrova, O. Yu. (2002) Statistical analysis of medical data: using of STATISTICA applied package [Statisticheskiy analiz meditsinskikh dannykh: primenenie paketa prikladnykh programm STATISTICA]. Moscow: MediaSfera. ISBN 5-90840134. [in Russian]

Soloviova, L. M. (2004) A comparative estimation of methods of diagnostics and therapy of hepatodystrophy in dogs [Porivnialna otsinka metodiv diahnostyky i terapii hepatodystrofii u sobak]. The dissertation thesis for the scientific degree of the candidate of veterinary sciences. Bila Tserkva: Bila Tserkva National Agrarian University. [in Ukrainian]

Starchenkov, S. V. (2001) Diseases of dogs and cats [Bolezni sobak i koshek]. Saint-Petersburg: Lan'. ISBN 5811404204. [in Russian]

Sysueva, A. V. (2009) Morphological and functional changes of red blood cells in liver pathologies in small domestic animals [Morfofunktsional’nye izmeneniya eritrotsitov krovi pri patologiyakh pecheni u melkikh domashnikh zhivotnykh]. The dissertation thesis for the scientific degree of the candidate of veterinary sciences. Moscow: Moscow State University of Applied Biotechnology. [in Russian]

Tennant, B. C. and Center, S. A. (2008) ‘Hepatic Function’, in Clinical Biochemistry of Domestic Animals. 6^th ed. Elsevier, pp. 379–412. http://dx.doi.org10.1016/B978-0-12-370491-7.00013-1

Vikulina, G. V. (2010) The state of connective tissue’s biopolymers and lipid’s exchange in clinically healthy and sick on bronchopneumonia young pigs [Stan biopolimeriv spoluchnoi tkanyny ta obminu lipidiv u klinichno zdorovykh i khvorykh na bronkhopnevmoniiu porosiat]. The dissertation thesis for the scientific degree of the candidate of veterinary sciences. Bila Tserkva: Bila Tserkva National Agrarian University. [in Ukrainian]

Xenoulis, P. G. and Steiner, J. M. (2010) ‘Lipid metabolism and hyperlipidemia in dogs’, The Veterinary Journal, 183(1), pp. 12–21. http://dx.doi.org10.1016/j.tvjl.2008.10.011

Xenoulis, P. G., Suchodolski, J. S., Levinski, M. D. and Steiner, J. M. (2008) ‘Serum liver enzyme activities in healthy Miniature Schnauzers with and without hypertriglyceridemia’, Journal of the American Veterinary Medical Association, 232(1), pp. 63–67. http://dx.doi.org10.2460/javma.232.1.63

Zagayko, A. L. (2009) Lipid metabolism and antioxidative-prooxidative state disorders under experimental metabolic syndrome [Porushennia obminu lipidiv ta prooksydantno-antyoksydantnykh protsesiv za eksperymentalnoho modeliuvannia metabolichnoho syndromu]. The dissertation thesis for the scientific degree of the doctor of biological sciences. Kyiv: Bogomolets National Medical University. [in Ukrainian]