Issue 2

Journal for Veterinary Medicine, Biotechnology and Biosafety

Volume 3, Issue 2, June 2017, Pages 10–13

ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)


Maslak Yu., Miroshnikova O., Fesenko I.

Kharkiv State Zooveterinary Academy, Kharkiv, Ukraine, e-mail:

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Citation for print version: Maslak, Yu., Miroshnikova, O. and Fesenko, I. (2017) ‘Clinical and biochemical aspects of diagnostics of Osteodystrophy of goats’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 3(2), pp. 10–13.

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Citation for online version: Maslak, Yu., Miroshnikova, O. and Fesenko, I. (2017) ‘Clinical and biochemical aspects of diagnostics of Osteodystrophy of goats’, Journal for Veterinary Medicine, Biotechnology and Biosafety. [Online] 3(2), pp. 10–13. Available at:

Summary. The purpose of this study was to carry out the comparative analysis of data of the clinical examination of goats and biochemical testing of bone tissue metabolism of the metabolites level in blood serum and urine for determination of criteria at diagnostics of osteodystrophy. The study was conducted on 20 adult goats. Diagnosis for osteodystrophy was made according to physical examination of goats and analysis of biochemical tests of bone tissue metabolism using blood serum and urine. Activity of aminotransferase (alanine aminotransferase, aspartate aminotransferase) and alkaline phosphatase and also concentration of glycoproteins (GP), chondroitin sulphate and fractional content of glucosaminoglicans content of total and ionized calcium were determined in blood serum. The content of hydroxyproline and total uronic acid were defined in urine. Comparative analysis of total clinical status of goats and level of biochemical components in blood serum and urine that characterize the connective tissue status at diagnostics of osteodystrophy was conducted. The intergroup significant differences of some biochemical parameters (aspartate aminotransferase, alkaline phisphatase, chondroitin sulphate in blood serum and fraction mucopolysaccharides, sum of fractions glucosaminoglicans in urine) were observed. Further testing must be conducted to determine the biochemical parameters in goat with subclinical signs of osteodystrophy.

Keywords: osteodystrophy, biochemical parameters, goats, blood serum, urine


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