Issue 3

Journal for Veterinary Medicine, Biotechnology and Biosafety

Volume 3, Issue 3, September 2017, Pages 18–25

ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)


Fedota O. M1, Ruban S. Yu. 2, Mitioglo L. V. 3, Tyzhnenko T. V. 1, Gontar Yu. V. 4, Lysenko N. G. 1

1 V. N. Karazin Kharkiv National University, Kharkiv, Ukraine, e-mail:

2 LLC ‘MPK Ekaterinoslavsky’, Dnipro, Ukraine

3 SE RFNyva’, Khrystynivka, Ukraine

4 LLC ‘Medical Center IGR’, Kyiv, Ukraine

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Citation for print version: Fedota, O. M., Ruban, S. Yu., Mitioglo, L. V., Tyzhnenko, T. V., Gontar Yu. V. and Lysenko, N. G. (2017) ‘Effects of dietary betaine on productive traits and reproductive health of dairy cows’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 3(3), pp. 18–25.

Download PDF (online version)

Citation for online version: Fedota, O. M., Ruban, S. Yu., Mitioglo, L. V., Tyzhnenko, T. V., Gontar Yu. V. and Lysenko, N. G. (2017) ‘Effects of dietary betaine on productive traits and reproductive health of dairy cows’, Journal for Veterinary Medicine, Biotechnology and Biosafety. [Online] 3(3), pp. 18–25. Available at:

Summary. Dietary supplementation of betaine may play an important role in productive and reproductive parameters of dairy cows. The aim of this study was to define the role of dietary betaine in dairy cows’ lactation. Cows were assigned to betaine or control groups according to the ‘case-control’ study design. Statistical methods included Pearson’s chi-squared and t criteria, Pearson and Spearman correlation coefficient r and ANOVA. We observed positive results after betaine diet correction of milk and reproductive traits of dairy cows in the heat stress conditions. Homocysteine level in blood of dairy cows is not depend on the age of the animals (r = 0.09), on the amount of lactation (r = 0.04), on a period after calving (r = –0.07). In this period higher milk yield was observed on lower homocysteine levels in the blood plasma of animals (r = –0.32). Also we found out that more inseminations were required for animals with a higher homocysteine level in the plasma (r = 0.36). After betaine supplementation milk fat concentration was higher in betaine-treated group of cows compared with control cows (3.05 vs 2.74%). Milk yield in betaine-treated group was in the negative correlation with milk fat (r = –0.67). An analysis of milk yields dynamics had showed that cows fed betaine had more stable and predictable milk yields per milking than controls (8.3 vs 40%) and milk yield in BET group was in a negative correlation with milk fat (r = –0,67). Negative dynamic of homocysteine level was noticed in a betaine group (27.5%) and positive (19.4%) — in the control group. More inseminations were required for cows of control group (1.8 vs 1.2).

Keywords: dairy cows, one-carbon metabolism, homocysteine, betaine, milk traits, reproduction


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