Issue 4

Journal for Veterinary Medicine, Biotechnology and Biosafety

Volume 3, Issue 4, December 2017, Pages 16–22

ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)

BONE MINERAL DENSITY IN EVALUATION THE PRODUCTIVE TRAITS AND REPRODUCTIVE HEALTH OF DAIRY COWS

Fedota O. M. 1, Babalian V. O. 2, Mitiohlo L. V. 3, Mazniakov S. M. 2, Valilshchikov M. V. 2, Tyzhnenko T. V. 1, Ruban S. Yu. 4

1 V. N. Karazin Kharkiv National University, Kharkiv, Ukraine, e-mail: amsfedota@gmail.com

2 Kharkiv Medical Academy of Postgraduate Education

3 SE RFNyva’, Khrystynivka, Ukraine

4 LLC ‘MPK Ekaterinoslavsky’, Dnipro, Ukraine

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Citation for print version: Fedota, O. M., Babalian, V. O., Mitiohlo, L. V., Mazniakov, S. M., Valilshchikov, M. V., Tyzhnenko, T. V. and Ruban, S. Yu. (2017) ‘Bone mineral density in evaluation the productive traits and reproductive health of dairy cows’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 3(4), pp. 16–22.

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Citation for online version: Fedota, O. M., Babalian, V. O., Mitiohlo, L. V., Mazniakov, S. M., Valilshchikov, M. V., Tyzhnenko, T. V. and Ruban, S. Yu. (2017) ‘Bone mineral density in evaluation the productive traits and reproductive health of dairy cows’, Journal for Veterinary Medicine, Biotechnology and Biosafety. [Online] 3(4), pp. 16–22. Available at: http://jvmbbs.kharkov.ua/archive/2017/volume3/issue4/oJVMBBS_2017034_016-022.pdf

Summary. Importance of studying osteoporosis and bone mineral density is due to the search for understanding on the regulation of bone mineral density, finding the signaling pathways and novel therapeutic targets, clarification of the gene network of osteoporosis. Since it is not always possible to assess the influence of various factors on the normal variation in bone mineral density, it is advisable to use animals as models. The aim of this study was evaluation of the bone mineral density and its relation with reproductive and productive characteristics of lactating dairy cows. Statistical methods included Pearson’s chi-squared and t criteria, Pearson’s and Spearmen correlation coefficient r and ANOVA. We analyzed the bone tissue indicators, productive and reproductive traits of dairy cows. The relation between health and reproduction traits of dairy cows — somatic cell count in milk, the open day, efficiency of insemination and the bone mineral density of cows was demonstrated. Also we found that bone mineral density was in a negative correlation with between somatic cell count in milk (r = –0.67), duration of open day (r = –0.50). More insemination was required for animals with a lower level of bone mineral density (r = –0.67). The level of bone mineral density is notified as independent from age, number of lactations and pregnancy, and the productivity of cows — milk yield, milk fat, milk protein. In the absence of the influence of chemical agents on metabolism, the processes of pregnancy and lactation are not a reason for reducing the bone mineral density in a balanced and high-grade diet.

Keywords: bone mineral density, dairy cows, milk traits, osteoporosis, reproduction of cows, somatic cell count

References:

Adlercreutz, H. and Mazur, W. (1997) ‘Phyto-oestrogens and Western Diseases’, Annals of Medicine, 29(2), pp. 95–120. http://dx.doi.org/10.3109/07853899709113696

Alam, I., Padgett, L. R., Ichikawa, S., Alkhouli, M., Koller, D. L., Lai, D., Peacock, M., Xuei, X., Foroud, T., Edenberg, H. J. and Econs, M. J. (2014) ‘SIBLING family genes and bone mineral density: Association and allele-specific expression in humans’, Bone, 64, pp. 166–172. http://dx.doi.org/10.1016/j.bone.2014.04.013

Atramentova, L. A. and Utevskaya, A. M. (2008) Statistical methods in biology [Statisticheskie metody v biologii]. Gorlovka: Lіkhtar. ISBN 9789662129267. [in Russian]

Bone, H. G., Greenspan, S. L., McKeever, C., Bell, N., Davidson, M., Downs, R. W., Emkey, R., Meunier, P. J., Miller, S. S., Mulloy, A. L., Recker, R. R., Weiss, S. R., Heyden, N., Musliner, T., Suryawanshi, S., Yates, A. J. and Lombardi, A. (2000) ‘Alendronate and estrogen effects in postmenopausal women with low bone mineral density 1’, The Journal of Clinical Endocrinology & Metabolism, 85(2), pp. 720–726. http://dx.doi.org/10.1210/jcem.85.2.6393

Boudin, E., Fijalkowski, I., Hendrickx, G. and Van Hul, W. (2016) ‘Genetic control of bone mass’, Molecular and Cellular Endocrinology, 432, pp. 3–13. http://dx.doi.org/10.1016/j.mce.2015.12.021

Coates, D. B., Dixon, R. M., Murray, R. M., Mayer, R. J. and Miller, C. P. (2016) ‘Bone mineral density in the tail-bones of cattle: effect of dietary phosphorus status, liveweight, age and physiological status’, Animal Production Science, 56(12), pp. 2054–2059. http://dx.doi.org/10.1071/AN16376

Gellersen, B., Kempf, R., Telgmann, R. and DiMattia, G. E. (1994) ‘Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma’, Molecular Endocrinology, 8(3), pp. 356–373. http://dx.doi.org/10.1210/mend.8.3.8015553

Hiney, K. M., Nielsen, B. D., Rosenstein, D., Orth, M. W. and Marks, B. P. (2004) ‘High-intensity exercise of short duration alters bovine bone density and shape’, Journal of Animal Science, 82(6), pp. 1612–1620. http://dx.doi.org/10.2527/2004.8261612x

Keene, B. E., Knowlton, K. F., McGilliard, M. L., Lawrence, L. A., Nickols-Richardson, S. M., Wilson, J. H., Rutledge, A. M., McDowell, L. R. and Van Amburgh, M. E. (2004) ‘Measures of bone mineral content in mature dairy cows’, Journal of Dairy Science, 87(11), pp. 3816–3825. http://dx.doi.org/10.3168/jds.S0022-0302(04)73521-3

Lee, Y. C., Raychaudhuri, S., Cui, J., de Vivo, I., Ding, B., Alfredsson, L., Padyukov, L., Costenbader, K. H., Seielstad, M., Graham, R. R., Klareskog, L., Gregersen, P. K., Plenge, R. M. and Karlson, E. W. (2009) ‘The PRL –1149 G/T polymorphism and rheumatoid arthritis susceptibility’, Arthritis and Rheumatism, 60(5), pp. 1250–1254. http://dx.doi.org/10.1002/art.24468

Li, B. Y., Yang, Y. M., Liu, Y., Sun, J., Ye, Y., Liu, X. N., Liu, H. X., Sun, Z. Q., Li, M., Cui, J., Sun, D. J. and Gao, Y. H. (2017) ‘Prolactin rs1341239 T allele may have protective role against the brick tea type skeletal fluorosis’, PLoS ONE, 12(2), p. e0171011. http://dx.doi.org/10.1371/journal.pone.0171011

Li, J. J., Wang, B. Q., Fei, Q., Yang, Y. and Li, D. (2016) ‘Identification of candidate genes in osteoporosis by integrated microarray analysis’, Bone and Joint Research, 5(12), pp. 594–601. http://dx.doi.org/10.1302/2046-3758.512.BJR-2016-0073.R1

Maetani, A., Itoh, M., Nishihara, K., Aoki, T., Ohtani, M., Shibano, K., Kayano, M. and Yamada, K. (2016) ‘Experimental assessment of bone mineral density using quantitative computed tomography in Holstein dairy cows’, Journal of Veterinary Medical Science, 78(7), pp. 1209–1211. http://dx.doi.org/10.1292/jvms.15-0642

Mori, G., D’Amelio, P., Faccio, R. and Brunetti, G. (2013) ‘The interplay between the bone and the immune system’, Clinical and Developmental Immunology, 2013(720504), pp. 1–16. http://dx.doi.org/10.1155/2013/720504

Özbaş, H., Onrat, S. T. and Özdamar, K. (2012) ‘Genetic and environmental factors in human osteoporosis’, Molecular Biology Reports, 39(12), pp. 11289–11296. http://dx.doi.org/10.1007/s11033-012-2038-5

Pellegrini, I., Lebrun, J. J., Ali, S. and Kelly, P. A. (1992) ‘Expression of prolactin and its receptor in human lymphoid cells’, Molecular Endocrinology, 6(7), pp. 1023–1031. http://dx.doi.org/10.1210/mend.6.7.1508218

Pietschmann, P., Mechtcheriakova, D., Meshcheryakova, A., Föger-Samwald, U. and Ellinger, I. (2016) ‘Immunology of osteoporosis: A mini-review’, Gerontology, 62(2), pp. 128–137. http://dx.doi.org/10.1159/000431091

Ray, K. (2014) ‘Bone: The immune system takes control of bone homeostasis’, Nature Reviews Rheumatology, 10(7), pp. 382–382. http://dx.doi.org/10.1038/nrrheum.2014.83

Rocha-Braz, M. G. M. and Ferraz-de-Souza, B. (2016) ‘Genetics of osteoporosis: Searching for candidate genes for bone fragility’, Archives of Endocrinology and Metabolism, 60(4), pp. 391–401. http://dx.doi.org/10.1590/2359-3997000000178

Shupe, J. L., Butcher, J. E., Call, J. W., Olson, A. E. and Blake, J. T. (1988) ‘Clinical signs and bone changes associated with phosphorus deficiency in beef cattle’, American Journal of Veterinary Research, 49(9), pp. 1629–1636. PMID: 3223676

Somekawa, Y., Chiguchi, M., Ishibashi, T. and Aso, T. (2001) ‘Soy intake related to menopausal symptoms, serum lipids, and bone mineral density in postmenopausal Japanese women’, Obstetrics and Gynecology, 97(1), pp. 109–115. http://dx.doi.org/10.1016/S0029-7844(00)01080-2

Stevens, A., Ray, D., Alansari, A., Hajeer, A., Thomson, W., Donn, R., Ollier, W. E. R., Worthington, J. and Davis, J. R. E. (2001) ‘Characterization of a prolactin gene polymorphism and its associations with systemic lupus erythematosus’, Arthritis and Rheumatism, 44(10), pp. 2358–2366. http://dx.doi.org/10.1002/1529-0131(200110)44:10<2358::AID-ART399>3.0.CO;2-K

Thomas, T. (2010) ‘Nouveaux acteurs du remodelage osseux, rôle du système immunitaire’, Bulletin de l’Academie Nationale de Medecine, 194(8), pp. 1493-4503. PMID: 22046712. Available at: http://www.academie-medecine.fr/wp-content/uploads/2013/03/2010.8.pdf. [in French]

Wei, P., Liu, M., Chen, Y. and Chen, D.-C. (2012) ‘Systematic review of soy isoflavone supplements on osteoporosis in women’, Asian Pacific Journal of Tropical Medicine, 5(3), pp. 243–248. http://dx.doi.org/10.1016/S1995-7645(12)60033-9

Williams, S. N., Lawrence, L. A., McDowell, L. R., Wilkinson, N. S., Ferguson, P. W. and Warnick, A. C. (1991) ‘Criteria to evaluate bone mineralization in cattle: I. Effect of dietary phosphorus on chemical, physical, and mechanical properties’, Journal of Animal Science, 69(3), pp. 1232–1242. http://dx.doi.org/10.2527/1991.6931232x

Wythe, S. E., Nicolaidou, V. and Horwood, N. J. (2014) ‘Cells of the immune system orchestrate changes in bone cell function’, Calcified Tissue International, 94(1), pp. 98–111. http://dx.doi.org/10.1007/s00223-013-9764-0

Zhang, X., Shu, X.-O., Li, H., Yang, G., Li, Q., Gao, Y.-T. and Zheng, W. (2005) ‘Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal women’, Archives of Internal Medicine, 165(16), pp. 1890–1895. http://dx.doi.org/10.1001/archinte.165.16.1890

Zhang, Y., Liu, H., Zhang, C., Zhang, T., Zhang, B., Li, L., Chen, G., Fu, D. and Wang, K. (2015) ‘Endochondral ossification pathway genes and postmenopausal osteoporosis: Association and specific allele related serum bone sialoprotein levels in Han Chinese’, Scientific Reports, 5(1), p. 16783. http://dx.doi.org/10.1038/srep16783

Zimin, A. V, Delcher, A. L., Florea, L., Kelley, D. R., Schatz, M. C., Puiu, D., Hanrahan, F., Pertea, G., Van Tassell, C. P., Sonstegard, T. S., Marçais, G., Roberts, M., Subramanian, P., Yorke, J. A. and Salzberg, S. L. (2009) ‘A whole-genome assembly of the domestic cow, Bos taurus’, Genome Biology, 10(4), p. R42. http://dx.doi.org/10.1186/gb-2009-10-4-r42