Issue 4

Journal for Veterinary Medicine, Biotechnology and Biosafety

Volume 4, Issue 4, December 2018, Pages 29–32

ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)


Kovalenko I. V. 1, Fotina T. I. 2, Fotina H. A. 2, Berezovskyi A. V. 2, Kovalenko V. L. 3, Fotin A. I. 2, Fotin O. V. 2

1 National Scientific Center ‘Institute of Experimental and Clinical Veterinary Medicine’, Kharkiv, Ukraine, е-mail:

2 Sumy National Agrarian University, Sumy, Ukraine, e-mail:

3 State Scientific Control Institute of Biotechnology and Strains of Microorganisms, Kyiv, Ukraine, e-mail:

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Citation for print version: Kovalenko, I. V., Fotina, T. I., Fotina, H. A., Berezovskyi, A. V., Kovalenko, V. L., Fotin, A. I. and Fotin, O. V. (2018) ‘Research of toxicity parameters of disinfectant ‘Sun Stim’’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 4(4), pp. 29–32.

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Citation for online version: Kovalenko, I. V., Fotina, T. I., Fotina, H. A., Berezovskyi, A. V., Kovalenko, V. L., Fotin, A. I. and Fotin, O. V. (2018) ‘Research of toxicity parameters of disinfectant ‘Sun Stim’, Journal for Veterinary Medicine, Biotechnology and Biosafety. [Online] 4(4), pp. 29–32. Available at:

Summary. Acute toxicity of set ‘Sun Stim’ was determined on laboratory animals in an experimental laboratory research. The disinfectant has high biological activity and low toxicity due to the active substance which is able to show a broad spectrum of activity against microorganisms. Based on the results, DL50 of the set for sanitation ‘Sun Stim’ for female rats 2,000.0 ± 35.0 mg/kg body weight, male — 2,033.0 ± 34.3 mg/kg. Thus, this drug, when injected into the stomach, according to the classification of toxicity in accordance with state standard (GOSТ 12.1.007-76), is allowed to be classified as III hazard class, low-hazard compounds. The set for sanitation ‘Sun Stim’ and the substances from which it was made do not have carcinogenic, mutagenic or genotoxic effects.

Keywords: ‘Sun Stim’, PGMG (polyhexamethylene guanidine hydrochloride), acute toxicity, laboratory animals, disinfectant


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