Journal for Veterinary Medicine, Biotechnology and Biosafety

Volume 6, Issue 1, January 2020, Pages 15–17

ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)


Zlenko O. B. 1, Ignatenkov O. S. 2, Vinokurova K. V. 2, Gerilovych A. P. 1

1 National Scientific Center ‘Institute of Experimental and Clinical Veterinary Medicine’, Kharkiv, Ukraine, e-mail:

2 Mykolaiv Regional Laboratory Center of the Ministry of Health of Ukraine, Mykolaiv, Ukraine

Download PDF (print version)

Citation for print version: Zlenko, O. B., Ignatenkov, O. S., Vinokurova, K. V. and Gerilovych, A. P. (2020) ‘Case report on the human infection with Tularemia in Mykolaiv Region, 2018’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 6(1), pp. 15–17.

Download PDF (online version)

Citation for online version: Zlenko, O. B., Ignatenkov, O. S., Vinokurova, K. V. and Gerilovych, A. P. (2020) ‘Case report on the human infection with Tularemia in Mykolaiv Region, 2018’, Journal for Veterinary Medicine, Biotechnology and Biosafety. [Online] 6(1), pp. 15–17. DOI: 10.36016/JVMBBS-2020-6-1-3.

Summary. The work aims to provide a study and report the case with a 47-year-old white man from urban-type settlement Oleksandrivka (Voznesensk District, Mykolaiv Region) diagnosed with pharyngitis, amygdalitis, polylymphoadenopathy, and buboadenitis caused by Francisella tularensis. The tularemia diagnosis in the patient was confirmed with agglutination test and western blot of patient’s blood serum in dilutions 1:100 and 1:200 respectively. The additional surveillance study (rodents, ticks, and water samples) in the surrounding area of the patient’s house showed positive results for F. tularensis in ticks in dilution 1:160++++

Keywords: Francisella tularensis, tularemia, zoonosis, ticks, Ukraine


Bevanger, L., Maeland, J. A. and Naess, A. I. (1988) ‘Agglutinins and antibodies to Francisella tularensis outer membrane antigens in the early diagnosis of disease during an outbreak of Tularemia’, Journal of Clinical Microbiology, 26(3), pp. 433–437. doi:

Byström, M., Böcher, S., Magnusson, A., Prag, J. and Johansson, A. (2005) ‘Tularemia in Denmark: Identification of a Francisella tularensis subsp. holarctica strain by real-time PCR and high-resolution typing by multiple-locus variable-number tandem repeat analysis’, Journal of Clinical Microbiology, 43(10), pp. 5355–5358. doi:

Hightower, J., Kracalik, I. T., Vydayko, N., Goodin, D., Glass, G. and Blackburn, J. K. (2014) ‘Historical distribution and host-vector diversity of Francisella tularensis, the causative agent of Tularemia, in Ukraine’, Parasites & Vectors, 7(1), p. 453. doi:

Hopla, C. E. (1974) ‘The ecology of Tularemia’, Advances in Veterinary Science and Comparative Medicine, 18, pp. 25–53. PMID:

McLendon, M. K., Apicella, M. A. and Allen, L.-A. H. (2006) ‘Francisella tularensis: Taxonomy, genetics, and immunopathogenesis of a potential agent of biowarfare’, Annual Review of Microbiology, 60(1), pp. 167–185. doi:

Oyston, P. C. F., Sjöstedt, A. and Titball, R. W. (2004) ‘Tularemia: Bioterrorism defence renews interest in Francisella tularensis’, Nature Reviews Microbiology, 2(12), pp. 967–979. doi:

Petersen, J. M. and Schriefer, M. E. (2005) ‘Tularemia: Emergence/re-emergence’, Veterinary Research, 36(3), pp. 455–467. doi:

Petersen, J. M., Schriefer, M. E., Gage, K. L., Montenieri, J. A., Carter, L. G., Stanley, M. and Chu, M. C. (2004) ‘Methods for enhanced culture recovery of Francisella tularensis’, Applied and Environmental Microbiology, 70(6), pp. 3733–3735. doi:

Rusev, I. T., Mogilevskiy, L. Ya., Boshchenko, Yu. A. and Zakusilo, V. N. (2005) ‘Biocenotic features of natural foci of Tularemia in the steppe zone of Ukraine’ [Biotsenoticheskie osobennosti prirodnykh ochagov tulyaremii stepnoy zony Ukrainy], Bulletin of Sumy State University. Medicine Series [Visnyk Sumskoho derzhavnoho universytetu. Seriia Medytsyna], 7, pp. 25–35. Available at: [in Russian]

Schmitt, P., Splettstösser, W., Porsch-Özcürümez, M., Finke, E.-J. and Grunow, R. (2005) ‘A novel screening ELISA and a confirmatory western blot useful for diagnosis and epidemiological studies of Tularemia’, Epidemiology and Infection, 133(4), pp. 759–766. doi:

Sjöstedt, A. (2007) ‘Tularemia: History, epidemiology, pathogen physiology, and clinical manifestations’, Annals of the New York Academy of Sciences, 1105(1), pp. 1–29. doi:

WHO (World Health Organisation) (2007) WHO Guidelines on Tularaemia. Geneva: WHO. Available at: