Issue 3

Journal for Veterinary Medicine, Biotechnology and Biosafety

Volume 2, Issue 3, October 2016, Pages 33–38

ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)


Gerilovych A. P., Stegniy B. T.

National Scientific Center ‘Institute for Experimental and Clinical Veterinary Medicine’, Kharkiv, Ukraine, e-mail:

Download PDF (print version)

Citation for print version: Gerilovych, A. P. and Stegniy, B. T. (2016) ‘Lumpy Skin Disease: Characterization and possible risks for Central and Eastern Europe’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 2(3), pp. 33–38.

Download PDF (online version)

Citation for online version: Gerilovych, A. P. and Stegniy, B. T. (2016) ‘Lumpy Skin Disease: Characterization and possible risks for Central and Eastern Europe’, Journal for Veterinary Medicine, Biotechnology and Biosafety. [Online] 2(3), pp. 33–38. Available at:

Summary. Lumpy skin disease (LSD, nodular dermatitis of cattle) — is the contagious poxviral disease of cattle. It is characterized by severe losses and different ranges of mortality and morbidity. The disease is endemic in many Asian and African countries. The article is devoted to explanation of LSD history, epizoothology, and distribution, risks associated with the disease, diagnostics, differential diagnostics and prevention. The situation regarding LSDV introduction to Ukraine is likely to be non-optimistic. Russia, Caucasian countries, and Bulgaria high LSD-associated risks put our territory on high range of risk regarding LSDV introduction. Disease introduction probabilities could be estimated as extremely high, and high from the side of Russia. NSC ‘IECVM’ in collaboration with SSRILDVSE developed the in house PCR-based protocol for LSDV detection that requires fast implementation. Joint collaboration in area of development regional LSDV distribution control policy and contingency plan are required.

Keywords: lumpy skin disease, risk analysis, epidemiology, diagnostics, animals


AHAW (EFSA Panel on Animal Health and Welfare) (2015) ‘Scientific opinion on lumpy skin disease’, EFSA Journal, 13(1), p. 3986.

Ali, A. A., Esmat, M., Attia, H., Selim, A. and Abdel-Humid, Y. M. (1990) ‘Clinical and pathological studies on lumpy skin disease in Egypt’, Veterinary Record, 127(22), pp. 549–550.

Ali, M. A. and Amina, A. D. (2013) ‘Abattoir-based survey and histopathological findings of Lumpy skin disease in cattle at Ismailia Abattoir’, International Journal of Bioscience, Biochemistry and Bioinformatics, 3(4), pp. 372–375.

Al‑Salihi, L. (2014) ‘Lumpy Skin disease: Review of literature’, Mirror of Research in Veterinary Sciences and Animals, 3(3), pp. 6–23. Available at:

APHL (Joint IAEA/FAO Animal Production and Health Laboratory) (2014) SOP/IAEA/FAO/Coprpoxvirus/PCR/Standard operation procedure for the detection of Coprpoxvirus. Seibersdorf, Austria: FAO/IAEA Agriculture and Biotechnology Laboratories

Bowden, T. R., Coupar, B. E., Babiuk, S. L., White, J. R., Boyd, V., Duch, C. J., Shiell, B. J., Ueda, N., Parkyn, G. R., Copps, J. S. and Boyle, D. B. (2009) ‘Detection of antibodies specific for sheeppox and goatpox viruses using recombinant capripoxvirus antigens in an indirect enzyme-linked immunosorbent assay’, Journal of Virological Methods, 161(1), pp. 19–29.

Carn, V. M., Kitching, R. P., Hammond, J. M. and Chand, P. (1994) ‘Use of a recombinant antigen in an indirect ELISA for detecting bovine antibody to capripoxvirus’, Journal of Virological Methods, 49(3), pp. 285–294.

Coetzer, J. A. W. (2004) ‘Lumpy skin disease’, in Coetzer, J. A. W. and Tustin, R. C. (eds.) Infectious diseases of livestock. 2nd ed. Cape Town, South Africa: Oxford University Press, pp. 1268–1276. ISBN 9780195761719

Davies, F. G. (1991) ‘Lumpy skin disease, an African capripox virus disease of cattle’, British Veterinary Journal, 147(6), pp. 489–503.

OIE (World Organisation for Animal Health) (2016) ‘Chapter 2.4.13. Lumpy skin disease’, in: Manual of diagnostic tests and vaccines for terrestrial animals (mammals, birds and bees). Paris: OIE. Available at:

Tulman, E. R., Afonso, C. L., Lu, Z., Zsak, L., Kutish, G. F. and Rock, D. L. (2001) ‘Genome of lumpy skin disease virus’, Journal of Virology, 75(15), pp. 7122–7130.

Tulman, E. R., Afonso, C. L., Lu, Z., Zsak, L., Sur, J.‑H., Sandybaev, N. T., Kerembekova, U. Z., Zaitsev, V. L., Kutish, G. F. and Rock, D. L. (2002) ‘The Genomes of Sheeppox and Goatpox viruses’, Journal of Virology, 76(12), pp. 6054–6061.

Tuppurainen, E. S. M. and Oura, C. A. L. (2011) ‘Review: Lumpy skin disease: An emerging threat to Europe, the Middle East and Asia’, Transboundary and Emerging Diseases, 59(1), pp. 40–48.

Wainwright, S., Idrissi, A. E., Mattioli, R., Tibbo, M., Njeumi, F. and Raizman, E. (2013) ‘Emergence of lumpy skin disease in the eastern Mediterranean basin countries’, EMPRES watch, 29, pp. 1–6

Woods, J. A. (1988) ‘Lumpy skin disease—A review’, Tropical Animal Health and Production, 20(1), pp. 11–17.