Journal for Veterinary Medicine, Biotechnology and Biosafety
Volume 5, Issue 2, June 2019, Pages 5–10
ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)
INFLUENCE OF BOVINE LEUKEMIA VIRUS ASSOCIATED WITH OTHER VIRAL INFECTIONS ON CATTLE IMMUNITY
Gorbatenko S. K., Zavgorodniy A. I., Korneikov O. M., Kovalenko L. V., Stegniy B. T., Bolotin V. I.
National Scientific Center ‘Institute of Experimental and Clinical Veterinary Medicine’, Kharkiv, Ukraine, e-mail: email@example.com
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Citation for print version: Gorbatenko, S. K., Zavgorodniy, A. I., Korneikov, O. M., Kovalenko, L. V., Stegniy, B. T. and Bolotin, V. I. (2019) ‘Influence of Bovine leukemia virus associated with other viral infections on cattle immunity’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 5(2), pp. 5–10.
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Citation for online version: Gorbatenko, S. K., Zavgorodniy, A. I., Korneikov, O. M., Kovalenko, L. V., Stegniy, B. T. and Bolotin, V. I. (2019) ‘Influence of Bovine leukemia virus associated with other viral infections on cattle immunity’, Journal for Veterinary Medicine, Biotechnology and Biosafety. [Online] 5(2), pp. 5–9. DOI: .
Summary. Comparative hematological and biochemical studies in heifers at the age of 6–8 months with different epizootic background revealed that the persistence of the association of viruses (causative agents of bovine leukemia, infectious bovine rhinotracheitis, bovine parainfluenza-3, and bovine viral diarrhea) negatively affect the status of immunocompetent cells. As the cell number of the macrophage-neutrophil group increases by 25–37%, their functional activity decreases. Significant shifts in the state of protein metabolism, the development of immunosuppression, and intensification of lipid peroxidation processes occur in the bodies of the infected animals, indicating a decrease in the natural resistance of these animals. Significant difference in the intensity of the specific immune response in the vaccinated against pneumoenteritis of the viral etiology animals from BLV-free and BLV-positive farms has not been established.
Keywords: bovine leukemia, infectious bovine rhinotracheitis, bovine parainfluenza-3, bovine viral diarrhea, vaccines, immunity, Ukraine
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