Issue 3
Journal for Veterinary Medicine, Biotechnology and Biosafety
Volume
1, Issue 3, September 2015, Pages 27–29
ISSN 2411-3174 (print version) ISSN 2411-0388
(online version)
STuDY Of DRuG-RESISTANT
TuBERCuLOSIS IN KHARKIV REGION, uKRAINE
Poteiko P. I. 1 , Gerilovich
A. P. 2 , Konstantynovska O. S. 1
, Rogozhin A. V. 1 , Sapko
S. A. 2 , Liashenko A. A. 1 , Solodiankin O. S. 2 , Bolotin
V. I. 2
1 Kharkov Medical Academy of Post-Graduate
Education, Kharkov, Ukraine, e-mail: kfp1930@ukr.net
2 National Scientific Center ‘Institute of Experimental and
Clinical Veterinary Medicine’, Kharkov, Ukraine
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PDF (print version)
Citation for print version: Poteiko, P. I., Gerilovich, A. P., Konstantynovska,
O. S., Rogozhin, A. V., Sapko,
S. A., Liashenko, A. A., Solodiankin,
O. S. and Bolotin, V. I. (2015) ‘Study of
drug-resistant tuberculosis in Kharkiv region,
Ukraine’, Journal for
Veterinary Medicine, Biotechnology and Biosafety,
1(3), pp. 27–29.
Download
PDF (online version)
Citation for online version: Poteiko,
P. I., Gerilovich, A. P., Konstantynovska,
O. S., Rogozhin, A. V., Sapko,
S. A., Liashenko, A. A., Solodiankin,
O. S. and Bolotin, V. I. (2015) ‘Study of
drug-resistant tuberculosis in Kharkiv region,
Ukraine’, Journal for
Veterinary Medicine, Biotechnology and Biosafety.
[Online] 1(3), pp. 27–29. Available at: http://jvmbbs.kharkov.ua/archive/2015/volume1/issue3/oJVMBBS_2015013_027-029.pdf
Summary. A total of 93 isolates from pulmonary tuberculosis (TB)
patients in Kharkiv region were characterized by drug
susceptibility testing and genotypic analyses (VNTR
using five exact tandem repeat loci). Obtained data demonstrated that the
Beijing genotype was the most common (in 64 cases) among studied strains.
Twelve isolates had individual VNTR profile. Among
all patients 41 (44%) were diagnosed as MDR TB and 52
(56%) — TB with extending resistance. The most common resistance of Mycobacterium tuberculosis was observed to streptomycin. The frequency of resistance to
kanamycin, 4-aminosalicylic
acid and ethionamide was revealed significantly higher
for LAM strain in compare to Beijing strain (p<0.05).
Keywords: tuberculosis,
Mycobacterium tuberculosis, strains, Kharkiv region, Ukraine, resistance, PCR
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