jvmbbs

Issue 3

Journal for Veterinary Medicine, Biotechnology and Biosafety

Volume 4, Issue 3, September 2018, Pages 24–27

ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)

STUDY OF THE EFFECT OF THE PREPARATION BASED ON THE BACTERIOCIN NISIN ON PATHOGENIC BACTERIA

Kucheruk M. D., Zasiekin D. A., Vygovska L. M., Ushkalov V. O.

National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine, e-mail: lnvygovska@gmail.com

Citation for print version: Kucheruk, M. D., Zasiekin, D. A., Vygovska, L. M. and Ushkalov, V. O. (2018) ‘Study of the effect of the preparation based on the bacteriocin nisin on pathogenic bacteria’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 4(3), pp. 24–27.

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Citation for online version: Kucheruk, M. D., Zasiekin, D. A., Vygovska, L. M. and Ushkalov, V. O. (2018) ‘Study of the effect of the preparation based on the bacteriocin nisin on pathogenic bacteria’, Journal for Veterinary Medicine, Biotechnology and Biosafety. [Online] 4(3), pp. 24–27. Available at: http://jvmbbs.kharkov.ua/archive/2018/volume4/issue3/oJVMBBS_2018043_024-027.pdf

Summary. The bactericidal effect of the nisin-based preparation on the bacterial cultures (Escherichia coli ATCC 25922 (F 50), Bacillus subtilis ATCC 6633, Staphylococcus aureus ATCC 25923, Listeria ivanovii АТСС 19119, Yersinia enterocolitica ATCC 23715) was studied in vitro. Two postbiotic concentrations were tested. Based on in vitro studies, the expressed antimicrobial effect of the test drug on Escherichia coli ATCC 25922 (F 50), Bacillus subtilis ATCC 6633, Staphylococcus aureus ATCC 25923 was established. In addition, postbiotic variant 1 was active in relation to Listeria ivanovii АТСС 19119, variant 2 — in relation to Yersinia enterocolitica ATCC 23715. The obtained results point to the prospect of further study of the postbiotics effect in vivo for the purpose of their application in the treatment of infections caused by pathogenic bacteria with acquired resistance to antibiotics.

Keywords: postbiotics, drug, strains, in vitro, sensitivity

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