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Journal for Veterinary Medicine, Biotechnology and Biosafety

Volume 11, Issue 1, January 2025, Pages 39–49

ISSN 2411-3174 (print version) ISSN 2411-0388 (online version)

VIROPHORY OF THE PIG’S MICROFLORA AS A PHENOMENON OF THE SOME PORCINE VIRAL INFECTIONS PERENNISATION

Buzun A. I. ¹, Kolchyk O. V. ¹, Rudenko Ye. V. ¹, Fotina T. I. ², Pass S. V. ³

¹ National Scientific Center ‘Institute of Experimental and Clinical Veterinary Medicine’, Kharkiv, Ukraine, e-mail: kolchyk-elena@ukr.net

² Sumy National Agrarian University, Sumy, Ukraine

³ Veterinary clinic ‘Optim-Vet’ Ltd, Kamianske, Dnipropetrovsk Region, Ukraine

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Citation for print version: Buzun, A. I., Kolchyk, O. V., Rudenko, Ye. V., Fotina, T. I. and Pass, S. V. (2025) ‘Virophory of the pig’s microflora as a phenomenon of the some porcine viral infections perennisation’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 11(1), pp. 39–49.

Download PDF (online version)

Citation for online version: Buzun, A. I., Kolchyk, O. V., Rudenko, Ye. V., Fotina, T. I. and Pass, S. V. (2025) ‘Virophory of the pig’s microflora as a phenomenon of the some porcine viral infections perennisation’, Journal for Veterinary Medicine, Biotechnology and Biosafety, 11(1), pp. 39–49. DOI: 10.36016/JVMBBS-2025-11-1-6.

Summary. The problem of the perennisation porcine viral infections/rooting their agents is far from clear understanding. The article proposes a mechanism for the rooting of porcine viral infections through the interaction of viruses with the porcine microbiome. This provision is standed on results of retrospectively examine the relationship between bacterial virophoria of the primary microbiological cultures and the enzootic foci formation on the model of two enzootic focies of porcine respiratory disease complex (PRDC) with including of agents of the Aujeszky’s disease (AD) and porcine circovirus infection (PCVI). There was studied 183 samples of primary bacterial cultures (BC) from samples of clinical and pathological materials taken from pigs during the outbreaks/‘PRDC red phases’ (‘exposed pigs’) and in ‘PRDC green phases’ (‘non-exposed pigs’). There AD agent virophoria detected in 29 bacterial samples (70.7%, BC from nasal mucus, semen, liver and spleen) and PCVI agent ― in 22 samples (59.5%, BC from nasal and vaginal mucus and lungs) were recorded in group of ‘exposed pigs’. But there only 5 from 142 bacterial samples (3.5%, BC exclusively in semen samples) was recorded in group of ‘unexposed pigs’ in both holdings as virophoric for AD agent and two from 20 samples as virophoric for PCV-2 (11.1%, BC from lung and vaginal mucus samples). In according EvansCounty calculation (Epi Info for Windows v. 7.1.5) these date did next significance odds rations (OR) and risk ration (RR) indexes (P = 99.99%): 16.12 ≤ OR = 43.17 ≤ 134.05 and 3.13 ≤ RR = 4.25 ≤ 5.77, respectively. In addition, there BC from 11 nasal swabs of pigs with clinical signs of PRDC in back-yard holdings after the lifting of the quarantine for African swine fever (ASF) was examined in PCR on ASF. The 5 BC samples revealed as virophoric. To further develop of the Kharkiv doctrine of the associated infections epizootiology the concept of switching the epidemic process into an endemic one in piggery through the direct interaction of viruses with the pig microbiome is proposed

Keywords: Aujeszky’s disease, porcine circoviral disease, African swine fever

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