Journal for Veterinary Medicine, Biotechnology and Biosafety
Volume
11, Issue 3, September 2025, Pages 3–8
ISSN 2411-3174 (print version) ISSN 2411-0388
(online version)
ENVIRONMENTAL
AND BIOETHICAL STANDARDS FOR THE TREATMENT OF METABOLIC ACIDOSIS IN WILD
ANIMALS: EXPERIENCE WITH THE USE OF SODIUM BICARBONATE
Sachuk R. M. 1,
Velesyk T. A. 1, Stravskyy Ya. S. 2,
Katsaraba O. A. 3, Barylo B. S. 3
1 Rivne State
Humanitarian University, Rivne, Ukraine, e-mail: sachuk.08@ukr.net
2 Ivan
Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
3 Stepan
Gzhytskyi National University of Veterinary Medicine and Biotechnologies of
Lviv, Lviv, Ukraine
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PDF (print version)
Citation for print version: Sachuk, R. M.,
Velesyk, T. A., Stravskyy, Ya. S., Katsaraba, O. A.
and Barylo, B. S. (2025) ‘Environmental and bioethical standards for the treatment of Metabolic
acidosis in wild animals: Experience with the use of sodium bicarbonate’,
Journal for Veterinary Medicine,
Biotechnology and Biosafety, 11(3), pp. 3–8.
Download
PDF (online version)
Citation for online version: Sachuk, R. M.,
Velesyk, T. A., Stravskyy, Ya. S., Katsaraba, O. A.
and Barylo, B. S. (2025) ‘Environmental and bioethical standards for the treatment of Metabolic
acidosis in wild animals: Experience with the use of sodium bicarbonate’,
Journal for Veterinary Medicine,
Biotechnology and Biosafety, 11(3), pp. 3–8. DOI: 10.36016/JVMBBS-2025-11-3-1.
Summary. The article presents the
results of a study on the effectiveness of the veterinary drug
‘Acidostop’ (60 mg/ml sodium bicarbonate) in treating
metabolic acidosis in European fallow deer (Dama dama) in semi-free
conditions. The study was conducted in aviaries on a private farm, utilizing
both clinical and laboratory methods. Typical symptoms of acidosis, such as
depression, diarrhea, and dehydration, were successfully alleviated within
three to seven days of treatment. A comparative analysis with a 5% sodium
bicarbonate solution revealed that ‘Acidostop’ has comparable
therapeutic efficacy, is well tolerated, and does not cause adverse effects.
The study was conducted in accordance with the requirements of GLP, GCP, and in
compliance with the European Convention for the Protection of Vertebrate
Animals. Special attention was paid to bioethical aspects: minimizing stress,
environmental safety, and humane treatment of animals. The drug is officially
registered in Ukraine for use in European fallow deer, has no analogues outside
the country, which emphasizes its scientific novelty. The study has practical
significance for ecology and veterinary medicine in conditions of semi-free
keeping of wild animals. It is also a valuable teaching material for the
educational programs ‘Ecology’, ‘Veterinary Medicine’,
and ‘Zoophysiotherapy’. The results obtained contribute to the
formation of an environmentally responsible approach to the treatment of
animals among students
Keywords: European fallow
deer, ‘Acidostop’, hematological and biochemical blood parameters
References:
Åkerfeldt, M. P.,
Gunnarsson, S., Bernes, G. and Blanco-Penedo, I. (2020)
‘Health and welfare in organic livestock production systems —
a systematic mapping of current knowledge’, Organic Agriculture, 11, pp. 105–132. doi: 10.1007/s13165-020-00334-y.
Bijl, H. and Csányi, S.
(2022) ‘Fallow deer (Dama dama) population and harvest changes in
Europe since the early 1980s’, Sustainability, 14(19),
p. 12198. doi: 10.3390/su141912198.
Campbell, T. A. and
VerCauteren, K. C. (2011) ‘Diseases and parasites [of white-tailed deer]’, in Hewitt, D. G. (ed.), Biology
and Management of White-Tailed Deer. Boca Raton: CRC Press,
pp. 219–249. Available at:
https://digitalcommons.unl.edu/icwdm_usdanwrc/1388.
CE (The Council of Europe). (1986) European Convention for the Protection of
Vertebrate Animals Used for Experimental and Other Scientific Purposes.
(European Treaty Series, No. 123). Strasbourg: The Council of Europe.
Available at: https://conventions.coe.int/treaty/en/treaties/html/123.htm.
CEC (The Council of the European Communities)
(2010) ‘Directive 2010/63/EU of the European Parliament and of the
Council of 22 September 2010 on the protection of animals used for
scientific purposes’, The Official
Journal of the European Communities, L 276, pp. 33–79.
Available at: http://data.europa.eu/eli/dir/2010/63/oj.
Di Minin, E.,
Clements, H. S., Correia, R. A.,
Cortés-Capano, G., Fink, C., Haukka, A.,
Hausmann, A., Kulkarni, R. and Bradshaw, C. J. A.
(2021) ‘Consequences of recreational hunting for biodiversity
conservation and livelihoods’, One Earth, 4(2), pp. 238–253. doi: 10.1016/j.oneear.2021.01.014.
Dougherty, N., Gartrell, B.,
Walsh, V., Chatterton, J. and Lenting, B. (2024) ‘Serial
changes in metabolic acid-base status in three species of anesthetized captive
large felid’, Journal of Zoo and Wildlife Medicine, 55(3), pp. 602–610. doi: 10.1638/2022-0072.
Faria, C. (2022) Animal Ethics in the
Wild: Wild Animal Suffering and Intervention in Nature. Cambridge
University Press. doi: 10.1017/9781009119948.
Fox, M. W. (1995) ‘Veterinary
bioethics: Ecoveterinary and ethoveterinary perspectives’, Veterinary
Research Communications, 19(1),
pp. 9–15. doi: 10.1007/bf01839247.
Huaman, J. L.,
Helbig, K. J., Carvalho, T. G., Doyle, M.,
Hampton, J., Forsyth, D. M., Pople, A. R. and
Pacioni, C. (2023) ‘A review of viral and parasitic infections in
wild deer in Australia with relevance to livestock and human health’, Wildlife
Research, 50(8–9),
pp. 593–602. doi: 10.1071/wr22118.
Hunchak, R. V.,
Pano, Y. P., Pepko, V. O., Sachuk, R. M. and
Katsaraba, O. A. (2024) ‘Investigation of the specific toxicity
of an analgesic agent for wild ungulates based on meloxicam’ [Doslidzhennia
spetsyfichnoi toksychnosti analhetychnoho zasobu dlia dykykh kopytnykh tvaryn
na osnovi meloksykamu], Scientific Messenger of Lviv National University of
Veterinary Medicine and Biotechnologies named after S. Z. Gzhytskyj,
26(115), pp. 93–100.
doi: 10.32718/nvlvet11514.
[in Ukrainian].
Kalábová, M.,
Rinn, R., Matejević, M., Marković, V.,
Kušta, T., Löwe, R. and Lazaridou, D. (2025)
‘Forests, wildlife, and economy: The role of hunting tourism in
Czechia’s sustainable forest management’, Frontiers in Forests
and Global Change, 8,
p. 1525311. doi: 10.3389/ffgc.2025.1525311.
Kotsiumbas, I. Ya. (ed.) (2009)
‘Comprehensive assessment of the
impact of veterinary drugs on the morphofunctional state of the immune system.
Methodological recommendations’
[Kompleksna otsinka vplyvu veterynarnykh
preparativ na morfofunktsionalnyi stan imunnoi systemy. Metodychni rekomendatsii]. Lviv. [in Ukrainian].
Kotsiumbas, I. Ya. (ed.) (2013) Clinical Studies of Veterinary Drugs and
Feed Additives [Klinichni doslidzhennia veterynarnykh preparativ ta kormovykh
dobavok]. Lviv: SAM. ISBN 9668714091. [in Ukrainian].
Kotsiumbas, I. Ya.,
Kosenko, Yu. M., Stetsko, T. I., Muzyka, V. P.,
Zhyla, M. I., Brezvyn, O. M., Ostapiv, N. V.,
Vezdenko, O. S. and Lisova, N. E. (2021) Guidelines for Conducting Clinical Trials of
Veterinary Drugs on Target Animal Species [Kerivnytstvo shchodo provedennia klinichnykh doslidzhen veterynarnykh
preparativ na tsilovykh vydakh tvaryn]. Lviv. [in Ukrainian].
Ny, V., Needham, T.,
Bartoň, L., Bureš, D., Kotrba, R.,
Musa, A. S. and Ceacero, F. (2023) ‘Effects of
immunocastration and supplementary feeding level on the performance and blood
biochemical markers of farmed yearling fallow deer (Dama dama)’, Journal of Animal Physiology and Animal
Nutrition, 107(5),
pp. 1158–1166. doi: 10.1111/jpn.13807.
Simmonds, R. C. (2017)
‘Chapter 4. Bioethics and animal use in programs of research,
teaching, and testing’, in Weichbrod, R. H., Thompson, G. A.
and Norton, J. N. (eds.) Management of Animal Care and Use
Programs in Research, Education, and Testing. 2nd ed. Boca
Raton: CRC Press, pp. 35–62. doi: 10.1201/9781315152189-4.
Sultana, S., Sultana, N.,
Islam, M., Pervin, M., Khan, M. A. I. and
Khan, M. A. H. N. A. (2021) ‘Zoonotic diseases
appeared to be a major hurdle to successful deer farming in Bangladesh’, Veterinary
World, 14(9),
pp. 2462–2472. doi: 10.14202/vetworld.2021.2462-2472.
Tajchman, K.,
Steiner-Bogdaszewska, Ż., Kowalczuk-Vasilev, E. and
Dąbrowski, R. (2019) ‘Effect of Ca and P supplementation on the
haematological parameters and content of selected minerals in the blood of
young farmed fallow deer males (Dama dama)’,
Biologia, 75(3),
pp. 401–411. doi: 10.2478/s11756-019-00310-2.
Tian, L., Li, X., Zheng, H.,
Wang, L., Qin, Y. and Cai, J. (2022) ‘Fisher discriminant
model based on LASSO logistic regression for computed tomography imaging
diagnosis of pelvic rhabdomyosarcoma in children’, Scientific Reports,
12(1), p. 15631. doi: 10.1038/s41598-022-20051-8.
Vicente, F.,
Rodríguez, M. L., Martínez-Fernández, A.,
Soldado, A., Argamentería, A., Peláez, M. and de
la Roza-Delgado, B. (2014) ‘Subclinical ketosis on dairy cows in
transition period in farms with contrasting butyric acid contents in
silages’, The Scientific World Journal, 2014, 1–4. doi: 10.1155/2014/279614.
Vlizlo, V. V. (ed.) (2012) Laboratory
Methods of Research in Biology, Animal Husbandry and Veterinary Medicine
[Laboratorni metody doslidzhen u biolohii, tvarynnytstvi ta veterynarnii
medytsyni]. Lviv: Spolom. ISBN 9769666656776. [in Ukrainian].
VRU (Verkhovna Rada Ukrainy) (2006) ‘Law
of Ukraine No. 3447-IV of
